Before and after radioactive iodine treatment for cats with hyperthyroidism

Two different cats in a cage

Sometimes, you have to see it to believe it. Radioactive iodine therapy is the gold standard treatment for cats with hyperthyroidism and the only curative solution. However, if you’ve not been in this position before, it may seem too good to be true. We sat down with Dr Rachel Korman to talk about the before, during and after of the process, and we’ve got some real patient case studies to share with you.

At Cat Specialist Services, our radioactive iodine facility in Brisbane offers world-class I-131 treatment. Every part of the hospital has been designed to support a comfortable stay and a low-stress recovery for our beautiful feline patients. Let’s take a closer look at the process and the results we’re seeing.

Before treatment, and the impact of hyperthyroidism on cats

Hyperthyroidism doesn’t always make itself obvious straight away. By the time a cat ends up at the hospital, the changes have often been building quietly for a while.“I think for a lot of owners, because it can often be a fairly gradual process, they’re not always aware of how far down the track those cats have gone,” says Dr Rachel Korman.

The clinical picture just prior to treatment is frequently a picture of an anxious, overstimulated and physically depleted feline. They may pace continuously, struggle to rest and show some signs of distress. “It’s like if you gave 20 cups of coffee to a toddler,” Dr Rachel explains. “That’s how they behave.”

Beyond behaviour, there’s the physical toll the condition takes on a cat. Weight loss is common, and in some cases severe, often seen alongside vomiting, diarrhoea and a dull, greasy coat. The constant activity can aggravate arthritis, particularly as this is a condition we typically see in older cats, and this further reduces their comfort. Some can even become reactive and aggressive, which is inconsistent with their usual temperament. That’s why it’s such a relief to welcome them into the hospital, where they can finally start heading toward a better quality of life.

three different cats inside a pet room

What it looks like during treatment

The stay itself can last anywhere from a week to just over three, depending on the cat’s needs and whether they come in for medical boarding. However, as Dr Rachel explains, “Often the hardest thing is just for owners to get their cats to the hospital. Catching them at home can be the hardest thing.” Once they’ve arrived and had time to settle, most cats cope far better than their owners expect.

Routine plays a big role in that adjustment. Predictability helps cats feel safe, and over time they begin to treat the hospital as their own space.

Patients can often be seen waiting at the front of their runs for breakfast, greeting staff and falling into familiar patterns. “They’re totally at home,” Dr Rachel says. “You can kind of see the way they interact… their routine is predictable and that’s really what a lot of cats love.”

Because an admission for I-131 isn’t a rushed visit, the team at CSS has time to build meaningful relationships with each patient. They learn who likes what, who prefers their medication in food, and who needs a bit more space or reassurance. It’s not just treatment. It’s feline care shaped by compassion and understanding.

Recovery and life after treatment

Once thyroid levels begin to settle, the difference in a cat’s demeanour is usually quite striking. The anxiety fades. Sleep returns. They’re more at ease in their bodies and more present in their surroundings. “Owners love it because they start getting their old cat back,” says Dr Rachel. “They’re calmer, less anxious, less worked up.”

The physical improvements tend to follow. Appetite returns. Coats become cleaner and softer. Behaviour transitions into something more familiar, less reactive and more affectionate. For many, it also brings relief from other issues that have either developed with age or been worsened by the thyroid disease itself, from gastrointestinal problems to heart changes. In some cases, follow-up scans even show measurable cardiac improvement. Dr Rachel recalls one patient whose heart wall thickness had “almost gone back to normal” just three months after treatment.

For many families, one of the most meaningful changes is being able to stop dealing with daily medications. Some cats were previously on a cocktail of thyroid, cardiac and anti-nausea drugs up to twice a day. “Owners can just be owners,” Dr Rachel says. “Not tablet givers.” And that simple change often brings the best kind of relief for everyone involved.

White and Fawn cat

Meet Bubba McNamara

Stacey first noticed something was off when Bubba, her usually relaxed indoor-outdoor cat, started hunting. It wasn’t like him. He’d also begun asking for food earlier in the day, and more often than usual. “He’s always been a hungry boy,” Stacey said, “but this was different.”

Fortunately, Stacey caught the changes early and, after discussing options with her vet, decided on I-131 treatment at Cat Specialist Services.

The change after treatment was clear. Bubba was more content, the hunting stopped, and his appetite settled back into its usual rhythm. His weight stabilised, and he returned to his easygoing self.

“It was a good experience, and I definitely recommend I-131. Even though others offer it, I recommend CSS. Everything from start to finish was just great.”

Dr Rachel recalls Bubba arriving a little anxious but settling in quickly. “He really relaxed into the environment,” she said. “By the end of his stay, he’d gained a few hundred grams and was eating well. He just looked really comfortable.”

Meet Kikki Cekalovic

Kiki had been living with poorly controlled hyperthyroidism, made more difficult by a suspected drug reaction and fluctuating thyroid levels on transdermal medication. Her case was further complicated by heart changes, which were picked up during her initial assessment. The team worked closely with a cardiologist to stabilise her before treatment, and she responded exceptionally well in hospital. Her three-month follow-up scan showed significant improvement.

Meet Kuro Chen

A calm and gentle older cat, Kuro had been managed medically for some time before his treatment. He had fluctuating T4 levels and a benign heart murmur, which was cleared by the cardiology team, and he went on to have a smooth stay. His thyroid levels normalised, and he gained nearly a kilo during his admission and he no longer needs ongoing heart medication.

Radioactive iodine treatment is life-changing for hyperthyroid cats and their owners

Radioactive iodine is a safe, non-invasive treatment that gives hyperthyroid cats a chance to return to who they were. For many, it means better health, more comfort and a calmer, medication-free life. “They start getting their old cats back,” says Dr Rachel. After months of managing a slow and stressful decline, that return is something families remember.

At Cat Specialist Services, we’ve administered this therapy to countless cats, and we never tire of seeing them regain their health and personality. The many before and after stories are deeply rewarding, and they’re exactly why we continue to do this work.

If you would like to learn more about our world-class radioactive iodine facility, speak with your regular vet about a referral or contact us at Cat Specialist Services today.

If you’re a veterinarian managing a cat with hyperthyroidism, you can refer them for specialised care here.

Are you worried about your cat’s health?

If you are concerned about your cat, please reach out to our friendly team. Call us on 1300 228 377 or fill out the contact form below. In an emergency, please contact your local vet.

For vets – to refer a patient or book a telehealth consultation, please call us on 1300 228 377, book through the portal or fill in the form.

Why do cats stay in hospital for so long during radioactive iodine treatment?

The treatment involves a short isolation period while the radioactive iodine works and any residual radiation levels drop to safe limits. Stays can range from about a week to just over three, depending on the cat and whether medical boarding is needed.

How do cats cope with staying in hospital?

Most cats settle in surprisingly well once they adjust. The team creates a predictable routine and gets to know each cat’s preferences, which helps them feel secure and comfortable.

What changes can I expect to see in my cat after treatment?

Many cats become calmer, less anxious and more sociable. Their appetite, coat, and behaviour improve as their thyroid levels return to normal. Some even show improvement in heart health or other conditions that had been worsened by hyperthyroidism.

Will my cat need any medication after treatment?

Most cats no longer need thyroid medication after radioactive iodine. In some cases, other medications they were on to manage secondary symptoms can also be reduced or stopped.

Why choose radioactive iodine over ongoing medication?

It’s a one-time, curative treatment that removes the need for daily pills and ongoing management, which improves life for both cats and their owners.

Patient Stories

Our commitment to feline health is best seen in the stories of the cats we’ve had the privilege of treating. These journeys highlight the dedication, expertise and compassion that drive us.

Each patient faced unique challenges, and it was our honour to offer high-quality care and help them regain strength and happiness. We value the deep bonds with cats and their owners, knowing the difference we make in their lives.

The road to recovery for Kuro

Kuro is a calm and dignified older cat who faced a challenging case of hyperthyroidism and early kidney changes.

Kikki’s transformation after I-131

Kikki is a gentle and resilient cat who came to CSS with a long-standing case of hyperthyroidism and significant heart changes.

Bubba beats hyperthyroidism

Bubba is a charming ginger and white cat who came to us after his owner noticed he was hunting more, eating voraciously and losing weight, all subtle signs of hyperthyroidism.

Expert care and a tailored plan saved Ed from pancreatitis

Pancreatitis is an inflammatory condition that disrupts digestion and often goes unnoticed until a cat becomes seriously ill. That was the case for Ed, whose vague symptoms progressed into a life-threatening emergency. Thankfully, with expert care from Cat Specialist Services, she made a full recovery.

Tango Triumphs Over FIP

At 5 months old, Tango was diagnosed with Feline Infectious Peritonitis (FIP). Once considered a fatal disease, the introduction of new treatments has significantly boosted the survival rate.

Contacting Us

Pet Owners
If you would like to talk about treatment for your cat, call us on 1300 228 377 or fill in the form.
In an emergency, please contact your local vet.

Vets and Nurses
To refer a patient or book a telehealth consultation please call us on 1300 228 377, book through the portal or fill in the form. For advice calls, please see the guidelines here.

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Saturday/Sunday - Closed

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